What is a clinical sign of heartworm disease in humans?

• A. Pulmonary nodules on the lungs
• B. Cough
• C. Fever
• D. Jaundice

Answer: (C)

In humans, heartworm disease most commonly presents as pulmonary nodules in the lungs. When the worms migrate to the lungs and die, they trigger localized granulomatous inflammation, which appears as nodular lesions on chest X-rays or CT scans. Many people have no symptoms, and the nodules are often found incidentally. Cough can occur but is nonspecific, and fever or jaundice are not typical features of this condition.